Specific inhibition of mouse oocyte nuclear protein phosphatase-1 stimulates germinal vesicle breakdown
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چکیده
منابع مشابه
Specific inhibition of mouse oocyte nuclear protein phosphatase-1 stimulates germinal vesicle breakdown.
Okadaic acid (OA)-induced germinal vesicle breakdown (GVBD) and localization of protein phosphatase-1 (PP1) in oocyte nuclei are suggestive of PP1's role in regulating oocyte GVBD. To explore this possibility, we microinjected protein phosphatase (PP) inhibitors OA, anti-PP1 antibody (anti-PP1), PP1 inhibitor I2, and anti-PP2A antibody (anti-PP2A) into nuclei of roscovitine (ROSC)-arrested mous...
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ژورنال
عنوان ژورنال: Molecular Reproduction and Development
سال: 2003
ISSN: 1040-452X,1098-2795
DOI: 10.1002/mrd.10258